• eTheRNA
  • Join us in our mission to bring hope to patients by developing novel immunotherapies

Careers

eTheRNA has entered a new phase in its young but promising history. The company is well positioned to complete phase I and II clinical studies with its mRNA-based TriMix platform for the treatment of advanced melanoma and breast cancer. eTheRNA plays a pioneering role in the development of mRNA-therapies that deliver tumor antigens to dendritic cells.

eTheRNA groups team members who are all passionate about mRNA technology and who wish to contribute to the development of truly innovative immunotherapies that can help millions of patients by combatting their disease.

Do you share our passion and are you the best in your area? Send us your spontaneous application.

Scientist Preclinical development

General Job Description

The Scientist Preclinical development is responsible for the design, planning and execution of programs within time and budget that are part of the preclinical development plan that fortify eTheRNAs IP position and enhance the clinical applicability of the TriMix platform, the key asset of eTheRNA, in accordance with the overall development strategy of the Company.

He/she will lead a number of programs dedicated to the design and pre-clinical evaluation of mRNA immunotherapies. She/he may supervise and manage Laboratory Technician(s) working on those projects. To do so, he/she will also establish and maintain a number of external collaboration and service relationships.

He/she will build and maintain a high level of scientific expertise in areas overall important for eTheRNA and specifically related to the programs he/she is accountable for.

A close interaction with the different preclinical, clinical and production groups at eTheRNA is essential.

He/she reports into the Senior scientist immune-engineering and works in partnership with CSO and the Preclinical Lead on the scientific validation, evaluation and presentation of results.

Responsibilities and Duties

The Scientist Preclinical R&D duties shall include, but not be limited to the following tasks with minimal assistance:

  • Managing programs and operations:
    • Planning and execution of research projects aimed at enhancing the immunogenicity of eTheRNA’s mRNA platform;
    • Supervision and execution of pre-clinical evaluation in animal models;
    • Key expert at the preclinical governance boards;
    • Propose creative but relevant research topics and approaches that can be turned into preclinical projects;
    • Design programs including time, resource and quality deliverables and defend them at governance;
    • Have a constant attention on protecting and generating IP from our research, and evolution of IP situation around the programs;
    • Establish partnerships and coordinates the work outsourced to Contract Research Organisations and Contract Laboratories;
    • Maintain a laboratory quality assurance program;
    • Suggest and draft grant applications and manuscripts.
  • Managing teams:
    • Supervise the activities of Laboratory Technician(s) for projects under his/her responsibility.
    • Stimulate cross-team interactions.
  • Managing science and participating to overall scientific debate:
    • Present research results at internal meetings and as a Company representative at local, national and international meetings;
    • Suggest ways to enhance clinical activity and applicability of eTheRNA‘s mRNA platforms;
    • Ensure up to date knowledge of the latest technologies, developments and science of the field by active follow-up of the scientific literature, participating to selected conferences and maintaining a network of peer and key experts;
    • Build/maintain a strong network of external industry and academic partners for collaborations, grant applications and access to new technologies.

Job Requirements

  • Education:
    • PhD or equivalent relevant experience in pharmaceutical sciences, biomedical sciences, bio engineering, biotechnology

  • Experience:
    • strong background in immunology, vaccinology and immunotherapy;
    • expert in the design and evaluation of nucleic acid delivery systems, including lipid based and polymeric delivery systems is considered a plus;
    • additional experience in infectious disease is regarded as valuable;
    • Minimum of 3 to 5 years of relevant laboratory experience (can be both academic or industrial);
    • Strong practical experience in a range of immunological techniques in vitro and in vivo studies;
    • Good knowledge of good laboratory quality assurance practices. GLP knowledge is a plus.

  • Other Qualifications, Skills and Abilities:
    • Detail-oriented, a problem solver with technical skills;
    • Demonstrated management, organizational and interpersonal skills;
    • Ability to solve problems and execute on initiatives;
    • Ability to work collaboratively and communicate effectively with technical staff;
    • Ability to independently integrate new information and approaches from the scientific literature;
    • Accuracy in following instructions, record keeping and completion of reports;
    • Program management;
    • Scientific integrity;
    • Fluent in English;
    • Well organized, well-structured, hands-on, result focused;
    • Ability to foster teamwork and a collaborative atmosphere;
    • Enthusiastic, flexible and able to multitask;
    • Ability to set priorities and take initiative;
    • Excellent understanding of MS Office (Excel, Word, PowerPoint, Outlook).

Offer

  • An exciting job in a dynamic and entrepreneurial environment with room for personal development;
  • Employment contract of unlimited duration with a competitive salary package.

Senior Scientist mRNA Formulation

General Job Description

The Senior Scientist mRNA Formulation will join the non-clinical team focused on the design and formulation of new mRNA-based immunotherapies. He/she will report into the [Principal Scientist Non-Clinical Development].

This position is based in eTheRNA’s laboratorium in Gent – Belgium.

Responsibilities and Duties

The Senior Scientist’s duties shall include, but not be limited to:

  • Planning and supporting projects to develop RNA delivery technology;
  • Development and characterizing of novel lipid and/or polymer based mRNA formulations;
  • Theoretical and practical drafting of scientific issues and matters relating to patent law in preclinical cellular and animal-experimental systems;
  • Drive scientific and technical innovation;
  • Lead a team of scientists and technicians and have an active role in the operations of the non-clinical team;
  • Technical staff training;
  • Manage multiple projects in mRNA delivery/formulation research involving cross-functional collaboration within therapeutic areas and across departments. Provide scientific expertise, guidance and strategy to successfully bring programs to Go/No Go decisions;
  • Development of relationships with pre-clinical contract research organizations and contract manufacturers, as well as managing collaborations with other (academic and industry) research centers;
  • Participate in authorship of scientific publications and patent applications;
  • Presenting results internally and externally.

Job Requirements

  • Education:
    • PhD in a life science-oriented discipline (e.g. chemistry, pharmacy, engineering) with a sound knowledge of the specialist aspects and methods involved in biochemistry, organic chemistry or pharmaceutics, or master's degree plus several years of professional experience or comparable qualification.

  • Experience:
    • 3+ years of relevant experience in companies engaged in biotech and/or pharmaceutical development;
    • Excellent knowledge of lipid-based formulation systems;
    • Deep knowledge on the design, physicochemical characterization and evaluation of nucleic acid delivery systems
    • Demonstrated track record of independent critical thinking and scientific achievement, as demonstrated by high impact publications and patents;
    • History of leading and contributing scientifically to discovery research programs;
    • Demonstrated ability to communicate complex data sets in a clear manner to internal and external stakeholders;
    • Strong analytical, problem-solving, and decision-making skills;
    • Strong academic and industry network in nucleic acid delivery;
    • Technical skills:
      • Experience in nanoparticle formulation (microfluidics, emulsification ..) methodologies and nanoparticle characterization techniques (DLS, zeta potential, chromatography);
      • Preferably experience in polymer and lipid synthesis, purification and characterization
      • Knowledge and/or experience with mRNA and miRNAs, lncRNAs or siRNA.

  • Other Qualifications, Skills and Abilities:
    • Detail-oriented with technical skills;
    • Demonstrated strong management, leadership, organizational and interpersonal skills;
    • Ability to solve problems and execute on initiatives;
    • Ability to work collaboratively and communicate effectively with R&D teams;
    • High level of integrity and dependability with a strong sense of urgency and results orientation;
    • Well organized, well-structured, hands-on, result focused;
    • Ability to foster teamwork and a collaborative atmosphere;
    • Enthusiastic, flexible and able to multitask;
    • Ability to set priorities and take initiative and be pro-active;
    • Fluent in English;
    • Excellent understanding of MS Office (Excel, Word, PowerPoint, Outlook).

Offer

  • An exciting job in a dynamic and entrepreneurial environment with room for personal development;
  • Employment contract of unlimited duration with a competitive salary package.

Senior Scientist Translational Immuno-Oncology

General Job Description

The Senior Scientist Translational Immuno-Oncology will join the non-clinical team focused on developing mRNA-based immunotherapies. He/she will report into the [Principal Scientist Non-Clinical Development].

This position is based in eTheRNA’s laboratorium in Gent – Belgium.

Responsibilities and Duties

The Senior Scientist’s duties shall include, but not be limited to:

  • Characterization of the tumor micro-environment in response to treatment with eTheRNA’s mRNA APIs;
  • Planning and implementation of studies to evaluate/validate the efficacy of eTheRNA’s mRNA APIs in humanized mice models;
  • Actively contribute to improve the efficacy of eTheRNA lead mRNA APIs;
  • Drive scientific and technical innovation;
  • Lead a team of scientists and technicians and have an active role in the operations of the non-clinical team;
  • Manage multiple projects in the immuno-oncology research involving cross-functional collaboration within therapeutic areas and across departments. Provide scientific expertise, guidance and strategy to successfully bring programs to Go/No Go decisions;
  • Development of relationships with pre-clinical contract research organizations and contract manufacturers, as well as managing collaborations with other (academic and industry) research centers;
  • Participate in authorship of scientific publications and patent applications;
  • Presenting results internally and externally.

Job Requirements

  • Education:
    • PhD in a life science-oriented discipline (e.g. chemistry, pharmacy, medicine), best with pharmaceutical development background, or master's degree plus several years of professional experience or comparable qualification.

  • Experience:
    • 3+ years of relevant experience in companies engaged in biotech and/or pharmaceutical development;
    • Strong background in human immunology, cancer immunotherapy and the biology of the tumor micro-environment;
    • Demonstrated track record of independent critical thinking and scientific achievement in the areas of immunology or oncology as demonstrated by high impact publications and patents;
    • History of leading and contributing scientifically to discovery research programs;
    • Demonstrated ability to communicate complex data sets in a clear manner to internal and external stakeholders;
    • Strong analytical, problem-solving, and decision-making skills;
    • strong academic and industry network in immuno-oncology;
    • Technical skills:
      • experience with a wide variety of assays to characterize the tumor micro-environment and the anti-tumor T cell response (multi-color flow cytometry, NanoString, Transcriptome profiling…);
      • experience with processing and analyzing primary patient tumor samples and/or experience with human immune cells processing;
      • experience with complex mice models to address anti-tumor efficacy (such as transgenic mice, mice with a reconstituted human immune system, …);
      • knowledge and/or experience with mRNA, miRNAs, lncRNAs and siRNA is considered a plus.

  • Other Qualifications, Skills and Abilities:
    • Detail-oriented with technical skills;
    • Demonstrated strong management, leadership, organizational and interpersonal skills;
    • Ability to solve problems and execute on initiatives;
    • Ability to work collaboratively and communicate effectively with R&D teams;
    • High level of integrity and dependability with a strong sense of urgency and results orientation;
    • Well organized, well-structured, hands-on, result focused;
    • Ability to foster teamwork and a collaborative atmosphere;
    • Enthusiastic, flexible and able to multitask;
    • Ability to set priorities and take initiative and be pro-active;
    • Fluent in English;
    • Excellent understanding of MS Office (Excel, Word, PowerPoint, Outlook).

Offer

  • An exciting job in a dynamic and entrepreneurial environment with room for personal development;
  • Employment contract of unlimited duration with a competitive salary package.

Communications Associate (part-time)

General Job Description

The Communications Associate will coordinate and support the internal and external communications of the Company and will thereby ensure that its messages are consistent.

The Communications Associate will be located in Niel and will work on a part-time basis.

The Communications Associate reports into the CEO.

Responsibilities and Duties

The Communications Associate performs a wide range of duties related to the internal and external communications, including but not be limited to:

  • Manage and implement the annual communications plan;
  • Own, develop, manage and ensure compliance with corporate identity;
  • Coordinate external communication activities and content with IR and PR service providers;
  • Develop and manage internal communications programs and generate content for these programs;
  • Creative content generation for mails, newsletters and other internal communications within the Company;
  • Prepare communications collateral for external audiences;
  • Assist in media opportunities and coordinating media inquiries;
  • Manage the Company’s website and create and implement social media activities;
  • Organize presentations and presences at congresses and other national/international meetings;
  • Partner closely with (i) internal team leads and (ii) external press and public relations agencies;
  • Ensure the internal and external communications are consistent and engaging;
  • Operate within a defined budget;
  • Monitor and prepare media activity reports;
  • Be the owner of all company materials with company logo.
  • Assist in the production process of print, electronic and multimedia materials.

Job Requirements

  • Education:
    • Bachelor (preference in media, Languages or Communication) or equivalent relevant experience.

  • Experience:
    • Minimum of 2 years of relevant experience in industrial B2B communications covering both PR and IR. An understanding of the life sciences industry is a plus.

  • Other Qualifications, Skills and Abilities:
    • Fluent in written and spoken English. Knowledge of Dutch is a plus;
    • Excellent verbal and written communication skills;
    • Strong knowledge of communication practices and techniques (incl. social media and digital marketing);
    • Autonomous, eager to learn, quick learning and have eye for detail;
    • Discreet and capable of handling confidential/sensitive information;
    • Ability to solve problems and execute on initiatives;
    • High level of integrity and dependability with a strong sense of urgency and results orientation;
    • Well organized, well-structured, hands-on, result focused;
    • Ability to foster teamwork and a collaborative atmosphere;
    • Enthusiastic, flexible and able to multitask;
    • Ability to set priorities and take initiative and be pro-active;
    • Excellent understanding of MS Office (Excel, Word, PowerPoint, Outlook).

Offer

  • An exciting job in a dynamic and entrepreneurial environment with room for personal development;
  • Employment contract of unlimited duration with a competitive salary package.

HR Administrator (part-time)

General Job Description

The HR Administrator is supporting the HR team. He/she acts as the first point of contact for HR-related queries from employees and external partners. The main administrative duties include maintaining personnel records, managing HR documents (e.g. employment records and onboarding guides), manage core HR processes and updating internal databases. He/she will work in close collaboration with the pay roll administrators (both internal and externa) and the HR manager.

The HR Administrator will be located in Niel and will work on a part-time basis.

The HR Administrator reports into the VP Corporate Development and General Counsel.

Responsibilities and Duties

The HR Administrator performs a wide range of administrative duties and shall include, but not be limited to:

  • Organize and maintain personnel records;
  • Update internal databases (e.g. record holiday, sick or maternity leave);
  • Prepare HR documents, like employment contracts and new hire guides;
  • Revise company HR related policies;
  • Support the recruitment processes;
  • Liaise with external partners, insurance vendors, and help to ensure legal compliance;
  • Create regular reports and presentations on HR metrics (e.g. turnover rates);
  • Answer employees queries about HR-related issues;
  • Assist payroll administrator by providing relevant employee information (e.g. leaves of absence, sick days and work schedules);
  • Assist in organizing individual and group training sessions and maintain training records;
  • Participate in HR projects (e.g. help organize a job fair event, team building events);
  • Provide administrative support to the HR function.

Job Requirements

  • Education:
    • Bachelor (preference in HR administration, Office Management, Languages or Communication) or equivalent relevant experience.

  • Experience:
    • Minimum of 2 years of relevant experience as HR Administrator with a good understanding of the HR-basics.

  • Other Qualifications, Skills and Abilities:
    • Excellent verbal and written communication skills;
    • Autonomous, eager to learn, quick learning and have eye for detail;
    • Discreet and capable of handling confidential/sensitive information;
    • Ability to solve problems and execute on initiatives;
    • High level of integrity and dependability with a strong sense of urgency and results orientation;
    • Well organized, well-structured, hands-on, result focused;
    • Ability to foster teamwork and a collaborative atmosphere;
    • Enthusiastic, flexible and able to multitask;
    • Ability to set priorities and take initiative and be pro-active;
    • Fluent in Dutch and English;
    • Excellent understanding of MS Office (Excel, Word, PowerPoint, Outlook).
  • Offer

    • An exciting job in a dynamic and entrepreneurial environment with room for personal development;
    • Employment contract of unlimited duration with a competitive salary package.

Research Associate Pre-Clinical Development

General Job Description

The Lab Technician Pre-Clinical Development is a hands-on person responsible for in vitro and in vivo tests and investigations in the field of immunotherapy. This position provides also input on the implementation, optimization and validation of new methods.

This position reports into the Principal Scientist, preclinical development.

This position will be based in Ghent.

Responsibilities and Duties

The Research Associate Pre-Clinical Development duties shall include, but not be limited to:

  • Perform, under general supervision, a variety of routine and specialized laboratory tests and animal experiments, specimen preparations and experimental procedures, assist in the use of specialized lab equipment and analysis of data generated by this equipment
  • Generation and characterization of formulations for mRNA delivery
  • Mice manipulations including injections (intravenous, intraperitoneal, subcutaneous), blood collection, induction of tumors and in vivo imaging
  • Analysis of harvested cells using techniques such as flow cytometry, ELISA, ELISPOT
  • Cell culture of human and murine cell lines and primary cells
  • Assist in the development of new assays
  • Help to troubleshoot experimental techniques, analyzing the data and reporting the experimental results
  • Maintain a detailed electronic lab book related to ongoing experiments
  • Participate in the maintenance of equipment and lab areas

Job Requirements

  • Education:
    • Professional Bachelor in Biomedical Laboratory Techniques or Master in Biomedical Sciences/Biotechnology or related field or equivalent relevant laboratory experience

  • Experience:
    • Minimum of two years of relevant laboratory experience (can be both academic or industrial)
    • Experience in cell culture and immunological assays
    • Experience in flow cytometry
    • Broad knowledge of molecular biotechnology techniques (cloning, DNA/RNA isolation, RT-QPCR, Western Blot)
    • Prior experience and interest in animal handling (FELASA B certificate mandatory)

  • Other Qualifications, Skills and Abilities:
    • Detail-oriented and accurate in following instructions, record keeping and completion of reports
    • Able to perform experimental troubleshooting and to propose technical solutions
    • Scientific integrity
    • Proficient in written and spoken English
    • Good communication skills
    • Well organized, well-structured, hands-on, result focused
    • Able to work under stringent time lines
    • Ability to foster teamwork and a collaborative atmosphere
    • Enthusiastic, flexible and able to multitask
    • Understanding of MS Office (Excel, Word, PowerPoint, Outlook)

Offer

  • An exciting job in a dynamic and entrepreneurial environment with room for personal development;
  • Employment contract of unlimited duration with a competitive salary package.